Dimethylaminopropionitrile
- CasNo:1738-25-6
Product Description
Buy Good Quality Dimethylaminopropionitrile 1738-25-6 with a minimum purity of 99%
- Molecular Formula: C5H10N2
- Molecular Weight: 98.1478
- Appearance/Colour: clear colorless liquid
- Vapor Pressure: 1.24mmHg at 25°C
- Melting Point: -43 °C(lit.)
- Refractive Index: n20/D 1.426(lit.)
- Boiling Point: 173.853 °C at 760 mmHg
- PKA: 8.17±0.28(Predicted)
- Flash Point: 62.778 °C
- PSA： 27.03000
- Density: 0.879 g/cm3
- LogP: 0.46168
Dimethylaminopropionitrile(Cas 1738-25-6) Usage
|
Production Methods |
3-Dimethylaminopropionitrile is derived from heating barium ethyl sulfate and KCN with subsequent distillation. |
|
Reactivity Profile |
Dimethylaminopropionitrile is combustible but non-flammable (flash point > 140°F), reacts with oxidizing agents (Hazardous Chemicals Desk Reference, p. 426 (1987)). Reacts violently with LIAlH4, a strong reducing agent. Emits toxic oxides of nitrogen and cyanide fumes when heated to decomposition. |
|
Safety Profile |
Poison by intravenous route. Moderately toxic by ingestion and skin contact. A skin and eye irritant. Flammable liquid when exposed to heat, flame, or oxidizers; can react with oxidizing materials. To fight fire, use foam, CO2, dry chemical. When heated to decomposition it emits highly toxic fumes of NOx and CN-. See also NITRILES. |
|
General Description |
Colorless liquid. Mp: -44.3°C; bp: 171-172°C. Density 0.87 g cm-3 at 20°C). Water-soluble. Used in the manufacture of polyurethane foam. Excessive exposure leads to urologic and neurologic disorders. |
InChI:InChI=1/C5H10N2/c1-7(2)5-3-4-6/h3,5H2,1-2H3/p+1
1738-25-6 Relevant articles
Addition of secondary amines to α,β-unsaturated carbonyl compounds and nitrites by using microstructured reactors
Loewe,Hessel,Lob,Hubbard
, p. 1144 - 1152 (2006)
Several additions of amines to α,β-unsat...
Cesium fluoride catalyzed Aza-Michael addition reaction in aqueous media
Labade, Vilas B.,Pawar, Shivaji S.,Shingare, Murlidhar S.
, p. 1055 - 1059 (2011)
A green approach to the Aza-Michael addi...
Decarboxylation reactions. III. Reaction of N,N' and N,O linked methylene compounds with carboxylic acids
Sekiya,Matsuda,Ito
, p. 1579 - 1585 (1975)
-
N-donor ligand as catalyst: A simple Aza-Michael addition reaction in aqueous media
Pawar, Shivaji S.,Dekhane, Deepak V.,Shingare, Murlidhar S.,Thore, Shivaji N.
, p. 1869 - 1873 (2008)
(Chemical Equation Presented) A novel ap...
Insights into Thiourea-Based Bifunctional Catalysts for Efficient Conversion of CO2to Cyclic Carbonates
Li, Zhuo-Qun,Zhang, Yao-Yao,Zheng, Yu-Jia,Li, Bo,Wu, Guang-Peng
, p. 3145 - 3155 (2022/02/14)
The bifunctional thiourea catalyst syste...
PREPARATION OF DIAMINE VIA THE PREPARATION OF AMINONITRILE
-
Paragraph 0126; 0127, (2014/02/15)
A continuous method (P) for preparing di...
Practical preparation of trimethoprim: A classical antibacterial agent
Ji, Ya-Fei,Jiang, Jian-An,Liu, Hong-Wei,Liao, Dao-Hua,Wei, Xian-Yong
supporting information, p. 1517 - 1522 (2013/05/22)
An efficient, simple, and mild preparati...
A novel photodegradable hyperbranched polymeric photoresist
Chatterjee, Saptarshi,Ramakrishnan
supporting information, p. 11041 - 11043 (2013/11/19)
We report the first synthesis of a photo...
1738-25-6 Process route
-
-
124-40-3
dimethyl amine
-
-
107-13-1,25014-41-9
acrylonitrile
-
-
1738-25-6
3-dimethylaminopropiononitrile
| Conditions | Yield |
|---|---|
|
In
water;
at 18 - 20 ℃;
for 5.5h;
Cooling with ice;
|
98%
|
|
In
water;
at 0 - 150 ℃;
for 5h;
|
98%
|
|
With
cesium fluoride;
In
water;
for 0.4h;
Sonication;
Irradiation;
|
94%
|
|
With
C9H14N2O3S;
In
water;
at 20 ℃;
for 0.5h;
|
93%
|
|
With
indium(III) chloride;
In
water;
1.) r.t., 10 min, 2.) r.t., 16 h;
|
92%
|
|
|
|
|
at 21.9 ℃;
Rate constant;
var. reagent ratios;
|
|
|
at 0 ℃;
|
|
|
In
water;
|
|
|
In
ethanol;
at 20 ℃;
for 12h;
|
|
|
With
water;
at 100 - 151 ℃;
under 750.075 - 3750.38 Torr;
Industry scale;
|
|
|
at 30 - 60 ℃;
for 4 - 16h;
under 3000.3 - 3750.38 Torr;
Product distribution / selectivity;
Industry scale;
Gas phase;
|
|
|
In
water;
at 60 - 70 ℃;
Product distribution / selectivity;
|
|
|
at 50 ℃;
for 1.2h;
|
|
|
In
water;
at 30 ℃;
for 16h;
|
95.6 %Chromat.
|
|
at 65 ℃;
under 375.038 Torr;
Industrial scale;
|
|
|
With
water;
|
|
|
|
-
-
potassium cyanide
-
-
1391906-41-4
2-(dimethylamino)ethyl ethyl carbonate
-
-
1738-25-6
3-dimethylaminopropiononitrile
| Conditions | Yield |
|---|---|
|
In
acetonitrile;
at 180 ℃;
for 4h;
Autoclave;
|
40%
|
1738-25-6 Upstream products
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dimethyl amine
-
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acrylonitrile
-
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