3-METHYL-1-(3-NITROPHENYL)-5-PYRAZOLONE
- CasNo:119-16-4
Product Description
3-METHYL-1-(3-NITROPHENYL)-5-PYRAZOLONE Good Supplier In Bulk Supply High Purity 119-16-4
- Molecular Formula:C10H9 N3 O3
- Molecular Weight:219.2
- Vapor Pressure:1.74E-07mmHg at 25°C
- Boiling Point:426.7°Cat760mmHg
- Flash Point:211.8°C
- PSA：78.49000
- Density:1.42g/cm3
- LogP:1.73120
3-METHYL-1-(3-NITROPHENYL)-5-PYRAZOLONE(Cas 119-16-4) Usage
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General Description |
3-METHYL-1-(3-NITROPHENYL)-5-PYRAZOLONE is a chemical compound with the molecular formula C10H8N4O3. It is a yellow crystalline solid that is commonly used as a reagent in organic synthesis and as an intermediate in the production of pharmaceuticals and dyes. 3-METHYL-1-(3-NITROPHENYL)-5-PYRAZOLONE is also used as a colorimetric reagent for the determination of certain metals, such as copper and bismuth, due to its ability to form colored complexes with these metals. Additionally, it has been studied for its potential anti-inflammatory and analgesic properties. However, it is important to handle this chemical with care, as it may pose health and environmental hazards. |
InChI:InChI=1/C10H9N3O3/c1-7-5-10(14)12(11-7)8-3-2-4-9(6-8)13(15)16/h2-4,6H,5H2,1H3
119-16-4 Relevant articles
One-flask synthesis of pyrazolone thioethers involving catalyzed and uncatalyzed thioetherification pathways of pyrazolones
Mukherjee, Prasun,Das, Asish R.
supporting information, p. 7267 - 7271 (2017/09/25)
A one-flask thioetherification of pyrazo...
Thrombopoietin mimetics
-
Page column 22, (2008/06/13)
Non-peptide TPO mimetics are disclosed, ...
Hydrazinonaphthalene and azonaphthalene thrombopoietin mimics are nonpeptidyl promoters of megakaryocytopoiesis
Duffy,Darcy,Delorme,Dillon,Eppley,Erickson-Miller,Giampa,Hopson,Huang,Keenan,Lamb,Leong,Liu,Miller,Price,Rosen,Shah,Shaw,Smith,Stark,Tian,Tyree,Wiggall,Zhang,Luengo
, p. 3730 - 3745 (2007/10/03)
High-throughput screening for the induct...
119-16-4 Process route
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141-97-9
ethyl acetoacetate
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619-27-2
3-nitrophenylhydrazine
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-
119-16-4
5-methyl-2-(3-nitrophenyl)-2,4-dihydro-pyrazol-3-one
| Conditions | Yield |
|---|---|
|
With
acetic acid;
at 100 ℃;
for 24h;
|
89% |
-
-
51516-96-2,636-95-3
3-nitrophenylhydrazine hydrochloride
-
-
141-97-9
ethyl acetoacetate
-
-
119-16-4
5-methyl-2-(3-nitrophenyl)-2,4-dihydro-pyrazol-3-one
| Conditions | Yield |
|---|---|
|
3-nitrophenylhydrazine hydrochloride;
With
sodium acetate;
In
ethanol; water;
at 20 ℃;
for 0.0833333h;
ethyl acetoacetate;
In
ethanol; water;
for 3h;
Reflux;
|
119-16-4 Upstream products
-
141-97-9
ethyl acetoacetate
-
619-27-2
3-nitrophenylhydrazine
-
51516-96-2
3-nitrophenylhydrazine hydrochloride
119-16-4 Downstream products
-
85094-18-4
1-(3-nitrophenyl)-3,4-dimethylpyrano<2,3-c>pyrazole-6(1H)-one
-
96138-43-1
3-[3-Methyl-1-(3-nitro-phenyl)-5-oxo-1,5-dihydro-pyrazol-(4Z)-ylidene]-butyric acid ethyl ester
-
90-32-4
2-(3-aminophenyl)-5-methyl-2,4-dihydro-pyrazol-3-one
-
165058-04-8
6-methoxy-3-methyl-1-(3-nitrophenyl)chromeno[2,3-c]pyrazol-4(1H)-one