2-Amino-3,5-dichloropyridine
- CasNo:4214-74-8
Product Description
Reliable factory customized supply 2-Amino-3,5-dichloropyridine 4214-74-8
- Molecular Formula: C5H4Cl2N2
- Molecular Weight: 163.006
- Appearance/Colour: Light beige to grey crystalline powder or flakes
- Vapor Pressure: 0.0507mmHg at 25°C
- Melting Point: 81-83 °C(lit.)
- Refractive Index: 1.6300 (estimate)
- Boiling Point: 235.2 °C at 760 mmHg
- PKA: 2.43±0.10(Predicted)
- Flash Point: 96 °C
- PSA： 38.91000
- Density: 1.497 g/cm3
- LogP: 2.55180
2-Amino-3,5-dichloropyridine(Cas 4214-74-8) Usage
InChI:InChI=1/C5H4Cl2N2/c6-3-1-4(7)5(8)9-2-3/h1-2H,(H2,8,9)/p+1
4214-74-8 Relevant articles
tert-BUTYLDIAZENE OXIDE AS A LEAVING GROUP
Filatov, I. E.,Kulikov, Yu. V.,Rusinov, G. L.,Pashkevich, K. I.
, p. 834 (1990)
-
One-pot chemoselective bis(suzuki-miyaura cross-coupling): Efficient access to 3,9-Bis[(hetero)aryl]-4H-pyrido[1,2-a]pyrimidin-4-one derivatives under microwave irradiation
Kabri, Youssef,Crozet, Maxime D.,Primas, Nicolas,Vanelle, Patrice
, p. 5595 - 5604 (2012)
A one-pot chemoselective bis(Suzuki-Miya...
Selectfluor-promoted regioselective chlorination/bromination of 2-aminopyridines and 2-aminodiazines using LiCl/LiBr
Hu, Jiao,Zhou, Gang,Tian, Yawei,Zhao, Xiaoming
supporting information, p. 6342 - 6345 (2019/07/10)
Using LiCl as a chlorine source, the chl...
A 2-amino -3,5-dichloro pyridine synthesis method
-
Paragraph 0027; 0028, (2017/03/14)
The invention belongs to the field of or...
CFBSA: a novel and practical chlorinating reagent
Lu, Zehai,Li, Qingwei,Tang, Minghua,Jiang, Panpan,Zheng, Hao,Yang, Xianjin
supporting information, p. 14852 - 14855 (2015/10/06)
A structurally simple, highly reactive c...
4214-74-8 Process route
-
-
1072-98-6
5-chloro-2-pyridylamine
-
-
4214-74-8
3,5-dichloropyridin-2-amine
| Conditions | Yield |
|---|---|
|
With
N-chloro-succinimide;
In
acetonitrile;
at 80 ℃;
for 16h;
|
79%
|
|
With
N-chloro-succinimide;
In
methanol; N,N-dimethyl-formamide;
at 45 ℃;
for 2.5h;
Temperature;
Solvent;
|
70.5%
|
|
With
ethanol; chlorine;
|
-
-
504-29-0
2-aminopyridine
-
-
4214-74-8
3,5-dichloropyridin-2-amine
| Conditions | Yield |
|---|---|
|
With
N-chloro-N-fluoro-benzenesulfonamide;
In
acetonitrile;
at 20 ℃;
|
84%
|
|
Multi-step reaction
with
2
steps
1: alcohol; chlorine
2: alcohol; chlorine
With
ethanol; chlorine;
|
|
|
With
chlorine;
In
hydrogenchloride;
|
|
|
With
hydrogenchloride; dihydrogen peroxide;
at 70 ℃;
for 2 - 4h;
|
4214-74-8 Upstream products
-
504-29-0
2-aminopyridine
-
1072-98-6
5-chloro-2-pyridylamine
-
16063-70-0
2,3,5-trichloropyridine
-
133520-09-9
N-tert-Butyl-N'-(3,5-dichloro-pyridin-2-yl)-diazene N'-oxide
4214-74-8 Downstream products
-
73447-01-5
2-[(3,5-dichloro-pyridin-2-ylimino)-methyl]-phenol
-
5437-33-2
3,5-Dichloro-2-pyridinol
-
116608-20-9
6-chloro-2-phenyl-thiazolo[4,5-b]pyridine
-
116608-17-4
N-(3,5-Dichloro-pyridin-2-yl)-thiobenzamide