• 图片1

L-LEUCYL-GLYCYL-GLYCINE

  • CasNo:1187-50-4

Product Description

Chinese factory supply L-LEUCYL-GLYCYL-GLYCINE 1187-50-4 in stock with high standard

  • Molecular Formula: C10H19N3O4
  • Molecular Weight: 245.279
  • Appearance/Colour: White crystalline powder 
  • Vapor Pressure: 1.17E-14mmHg at 25°C 
  • Melting Point: ~220 °C (dec.) 
  • Refractive Index: 1.504 
  • Boiling Point: 573.7 °C at 760 mmHg 
  • PKA: 3.30±0.10(Predicted) 
  • Flash Point: 300.8 °C 
  • PSA： 121.52000 
  • Density: 1.199 g/cm3 
  • LogP: 0.15890 

L-LEUCYL-GLYCYL-GLYCINE(Cas 1187-50-4) Usage

Definition

ChEBI: A tripeptide composed of one L-leucine and two glycine residues joined in sequence.

InChI:InChI=1/C10H19N3O4/c1-6(2)3-7(11)10(17)13-4-8(14)12-5-9(15)16/h6-7H,3-5,11H2,1-2H3,(H,12,14)(H,13,17)(H,15,16)

1187-50-4 Relevant articles

Racemic separation of the leucyl-glycyl-glycine ethyl ester.

LOSSE

, p. 257 - 259 (1958)

-

Peptide syntheses with mixed anhydrides from N-acyl-amino acids and saccharin

Micheel,Lorenz

, p. 242 - 252 (2007/10/05)

-

1187-50-4 Process route

<i>N</i>-[<i>N</i>-(<i>N</i>-benzyloxycarbonyl-L-leucyl)-glycyl]-glycine
14297-22-4

N -[N -(N -benzyloxycarbonyl-L-leucyl)-glycyl]-glycine

L-Leu-Gly-Gly
1187-50-4,3146-41-6,4337-37-5,18625-22-4

L-Leu-Gly-Gly

Conditions
Conditions Yield
With methanol; palladium; acetic acid; Durch Hydrogenolyse;
N-benzyloxycarbonyl-L-leucine methyl ester
51021-87-5

N-benzyloxycarbonyl-L-leucine methyl ester

L-Leu-Gly-Gly
1187-50-4,3146-41-6,4337-37-5,18625-22-4

L-Leu-Gly-Gly

Conditions
Conditions Yield
Multi-step reaction with 5 steps
1: hydrazine hydrate / 20 °C
2: aqueous HCl; acetic acid; NaNO2 / unter starker Kuehlung
3: diethyl ether; chloroform / 45 °C
4: aqueous methanol. NaOH
5: palladium; methanol; glacial acetic acid / Durch Hydrogenolyse
With hydrogenchloride; methanol; sodium hydroxide; diethyl ether; chloroform; hydrazine hydrate; palladium; acetic acid; sodium nitrite;

1187-50-4 Upstream products

  • 100348-21-8
    100348-21-8

    Leu-Gly-Gly-OEt

  • 14297-22-4
    14297-22-4

    N -[N -(N -benzyloxycarbonyl-L-leucyl)-glycyl]-glycine

  • 627-74-7
    627-74-7

    glycylglycine ethyl ester

  • 3190-70-3
    3190-70-3

    L-leucine N-carboxyanhydride

1187-50-4 Downstream products

  • 61-90-5
    61-90-5

    L-leucine

  • 686-50-0
    686-50-0

    L-leucyl-glycine

  • 141-43-5
    141-43-5

    ethanolamine

  • 556-50-3
    556-50-3

    glycylglycine

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