3-nitro-2,6-xylidine
- CasNo:67083-28-7
Product Description
Chemical plants supply high-quality 3-nitro-2,6-xylidine 67083-28-7 in bulk
- Molecular Formula: C8H10N2O2
- Molecular Weight: 166.18
- Vapor Pressure: 0.000195mmHg at 25°C
- Melting Point: 81-82℃
- Boiling Point: 328°C at 760 mmHg
- PKA: 2.19±0.10(Predicted)
- Flash Point: 152.2°C
- PSA： 71.84000
- Density: 1.22g/cm3
- LogP: 2.89820
3-nitro-2,6-xylidine(Cas 67083-28-7) Usage
|
General Description |
3-Nitro-2,6-xylidine is an organic chemical compound with the molecular formula C8H9NO2. It is a yellow crystalline solid that is primarily used in the production of dyes, pigments, and other organic compounds. 3-Nitro-2,6-xylidine is also used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It is a toxic and potentially hazardous substance that can cause irritation to the skin, eyes, and respiratory system upon contact or inhalation. Due to its potential health and environmental risks, proper handling, storage, and disposal procedures must be followed when working with 3-nitro-2,6-xylidine. |
InChI:InChI=1/C8H10N2O2/c1-5-3-4-7(10(11)12)6(2)8(5)9/h3-4H,9H2,1-2H3
67083-28-7 Relevant articles
Conformational control of bis-urea self-assembled supramolecular pH switchable low-molecular-weight hydrogelators
Chippindale, Ann M.,Christie, William,Gavriel, Alexander G.,German, Ian M.,Hayes, Wayne,O'Donnell, Adam D.
, (2021/11/03)
We report the synthesis and investigatio...
Enantiospecific Synthesis of Nepetalactones by One-Step Oxidative NHC Catalysis
Harnying, Wacharee,Neud?rfl, J?rg-M.,Berkessel, Albrecht
supporting information, p. 386 - 390 (2020/02/04)
An efficient oxidative NHC-catalyzed one...
Cell-Based Optimization of Covalent Reversible Ketoamide Inhibitors Bridging the Unprimed to the Primed Site of the Proteasome β5 Subunit
Stubba, Daniel,Bensinger, Dennis,Steinbacher, Janika,Proskurjakov, Lilia,Salcedo Gómez, álvaro,Schmidt, Uwe,Roth, Stefan,Schmitz, Katja,Schmidt, Boris
supporting information, p. 2005 - 2022 (2019/11/22)
The ubiquitin-proteasome system (UPS) is...
Discovery of a Chemical Probe Bisamide (CCT251236): An Orally Bioavailable Efficacious Pirin Ligand from a Heat Shock Transcription Factor 1 (HSF1) Phenotypic Screen
Cheeseman, Matthew D.,Chessum, Nicola E. A.,Rye, Carl S.,Pasqua, A. Elisa,Tucker, Michael J.,Wilding, Birgit,Evans, Lindsay E.,Lepri, Susan,Richards, Meirion,Sharp, Swee Y.,Ali, Salyha,Rowlands, Martin,O’Fee, Lisa,Miah, Asadh,Hayes, Angela,Henley, Alan T.,Powers, Marissa,Te Poele, Robert,De Billy, Emmanuel,Pellegrino, Loredana,Raynaud, Florence,Burke, Rosemary,Van Montfort, Rob L. M.,Eccles, Suzanne A.,Workman, Paul,Jones, Keith
, p. 180 - 201 (2017/04/26)
Phenotypic screens, which focus on measu...
67083-28-7 Process route
-
-
87-62-7
2,6-dimethylaniline
-
-
67083-28-7
2,6-dimethyl-3-nitroaniline
| Conditions | Yield |
|---|---|
|
With
sulfuric acid; nitric acid;
at 0 - 20 ℃;
for 2h;
|
89%
|
|
With
sulfuric acid; nitric acid;
at 0 - 20 ℃;
for 1h;
|
83%
|
|
With
sulfuric acid; nitric acid;
at 0 - 20 ℃;
for 12h;
|
81%
|
|
With
sulfuric acid; nitric acid;
for 0.166667h;
Ambient temperature;
|
66%
|
|
With
sulfuric acid; nitric acid;
at 20 ℃;
for 0.5h;
Cooling with ice;
|
33%
|
|
With
sulfuric acid; nitric acid;
|
|
|
With
sulfuric acid; nitric acid;
|
|
|
Multi-step reaction
with
3
steps
1: 97 percent
2: 80 percent / 65percent HNO3
/ acetic acid; H2
SO4
/ 1 h / Ambient temperature
3: 80 percent / 70percent aq. H2
SO4
/ 115 h / 120 °C
With
sulfuric acid; nitric acid;
In
sulfuric acid; acetic acid;
|
|
|
2,6-dimethylaniline;
With
sulfuric acid; nitric acid;
at 10 - 15 ℃;
for 0.666667h;
With
sodium hydroxide; water;
at 0 - 10 ℃;
|
-
-
5416-12-6
N-(2,6-dimethyl-3-nitro-phenyl)acetamide
-
-
67083-28-7
2,6-dimethyl-3-nitroaniline
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
methanol;
for 48h;
Heating / reflux;
|
99%
|
|
With
sulfuric acid;
at 120 ℃;
for 115h;
|
80%
|
|
N-(2,6-dimethyl-3-nitro-phenyl)acetamide;
With
sulfuric acid;
In
ethanol;
for 96h;
Reflux;
With
sodium hydroxide;
In
ethanol;
at 20 ℃;
|
55%
|
|
Verseifung;
|
67083-28-7 Upstream products
-
855227-16-6
benzenesulfonic acid-(2,6-dimethyl-3-nitro-anilide)
-
5416-12-6
N-(2,6-dimethyl-3-nitro-phenyl)acetamide
-
87-62-7
2,6-dimethylaniline
-
143032-15-9
1,7-Dimethyl-4-nitro-1,3-dihydro-benzo[c]isothiazole 2,2-dioxide
67083-28-7 Downstream products
-
35113-96-3
2-chloro-1,3-dimethyl-4-nitrobenzene
-
603-02-1
2,4-dinitro-m-xylene
-
60956-25-4
2-bromo-1,3-dimethyl-4-nitrobenzene
-
6994-63-4
2,6-dimethyl-3-nitro-phenol